The sex differences that impact the strength of your immune system

There are gender differences that favor or disfavor the risk of various diseases, including cancer and autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.

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January 31, 2023

MANILA, PHILIPPINES - AUGUST 19: Commuters are seen wearing face masks and face shields inside a bus in Quezon City, Metro Manila, Philippines on August 19, 2020. President Rodrigo Duterte has eased quarantine measures in the Philippine capital to boost the country's tank economy despite the highest number of coronavirus cases in Southeast Asia. The Philippines' Ministry of Health has so far confirmed 173,774 cases of coronavirus, a third of which were recorded in the past two weeks.  (Photo by Ezra Akayan/Getty Images)

Being male is a significant risk factor for severe COVID-19

Ezra Akayan/Getty Images

The concept of the “male flu” – the idea that men catch too many colds – is an old joke. Being male was a risk factor for experiencing more severe symptoms of coronavirus: in the UK in 2020, men were about 60% more likely to die from covid-19 than women. are almost twice as likely to be diagnosed with tuberculosis and slightly more likely to die from the flu. So, does your gender give you an advantage or disadvantage when it comes to immunity?

There are several possible reasons for gender differences in immunity. For one thing, in recent years it has been discovered that estrogen, the main female sex hormone, broadly stimulates the activity of the immune system. force is also at work.

Gender is controlled by DNA packaged into 23 pairs of chromosomes. Most females have her two X chromosomes, while most males have one X chromosome and her one Y chromosome.

This article is part of a special series on immunity.

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