Clovibactin: Superbugs will struggle to evolve resistance to unusual new antibiotic

Illustration of methicillin-resistant Staphylococcus aureus (MRSA) bacteria

Katerina Kong/Science Photo Library

Potential new antibiotics are highly effective against “superbugs” such as MRSA that are resistant to many existing antibiotics, and kill bacteria in unusual ways, so the evolution of resistance is very rapid. It becomes difficult.

Clovibactin, an antibiotic, was discovered from a rare bacterium isolated from sandy soil collected in North Carolina. Markus Weingers and his colleagues at Utrecht University in the Netherlands are studying how it works, with promising results. “Activity is even better than gold…

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